Metrology challenges in the biological environment

Description: Further challenges in the biological environment • Most biomolecules exist in an aqueous environment, which is not particularly suitable for force or electron microscopy. New techniques are therefore needed for in vivo measurements • For example, fluorescence resonance energy transfer (FRET) has been used to provide measurement of distances between fluorophores between 1nm and 10nm. • The fluorophores can be attached to biological molecules and can be used to give indications of distances between actives sites or interacting molecules, such as proteins and ligands, proteins to other proteins, or DNA interactions • Current advances on FRET such as plasmon coupling Emerging Nanomedical Applications and Their Metrology Needs Author: Richard Moore, Institute of Nanotechnology

Upload Date: 17-Mar-2010

View Count: 694

Reference URL: http://medical.wesrch.com/pdfME1XXFM1CPTJG

Short URL: http://www.wesrch.com/wiki1003

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