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1) orthopedic prostheses such as total knee and hip joint replacements, spinal implants, bone
fixators, and tendon and ligament prostheses;
2) cardiovascular implants such as artificial heart valves, vascular grafts and stents, pacemakers,
and implantable defibrillators;
3) neural implants (e.g., cochlear implants) and cerebrospinal fluid drainage systems (e.g.,
4) plastic and reconstructive implants such as breast augmentation or reconstruction,
maxillofacial reconstruction, artificial larynx, penile implants, and injectable collagen for soft
5) dental implants to replace teeth/root systems and bony tissue in the oral cavity;
6) ophthalmic systems including contact and intraocular lenses;
7) catheters and bladder stimulators;
8) drug-dispensing implants such as insulin pumps;
9) general surgical systems such as sutures, staples, adhesives, and blood substitutes. Nanotechnology in Medical Research
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