Vesalius annotations and the rise of early modern medicine
Next time you are in a library, open a random 16th-century book. There is a good chance that it contains a number of early handwritten annotations, underlinings, and haphazard jottings. Most books printed before 1600 were marked up by their readers in such a manner. A careful study of these annotations can reveal how readers responded to books, and what impact printed books had on the early modern world. We can examine how studiously the composer Johann Sebastian Bach read his Bible, and how much the protestant reformer Martin Luther disliked his contemporary author Erasmus of Rotterdam, writing "You are crazy? on the margins of Erasmus' edition of the New Testament.
Children conceived by medically assisted reproduction face an elevated risk of adverse birth outcomes. However, our results indicate that this increased risk is largely attributable to factors other t
In the four decades since the first birth by in-vitro fertilisation (IVF),1 the field has been rewarded with a Nobel prize,2 seen IVF evolve from an experimental procedure into clinical routine, and w
When a child is diagnosed with a life-threatening condition, one of the most challenging tasks facing health-care professionals is how to communicate this to the child, and to their parents or caregiv
A spate of violent attacks is threatening the Ebola virus response in DR Congo. Experts say the humanitarians and governments need to on community grievances. Andrew Green reports.
Kohei Shitara and colleagues (July 14, 2018, p 123)1 claimed that the treatment effect of pembrolizumab was greatest in patients with an Eastern Cooperative Oncology Group (ECOG) performance status of
A food-systems approach would have substantial benefits in policy making, whether in businesses or governments. Thinking systemically and at an interdisciplinary level can help ensure that challenges
Addressing an American audience, I quoted childhood poverty figures from UNICEF that show 29% of children in the USA grow up in poverty, more like Mexico than the Nordic countries at 9-11%. Somewhat o
DR Congo is currently facing its tenth outbreak of Ebola virus disease (EVD) since the virus was discovered in 1976. As of March 3, 2019, there were 897 confirmed cases, with 563 deaths (including con
We thank Fei Liang for highlighting the CONSORT recommendation to do interaction tests when investigating subgroup analyses.
Commitment to "defend all of the rights of the child? as a pillar for ensuring child health has a contemporary and global timbre to it. But this aspiration, which is enshrined in the 1989 UN Conventio
To support the development, approval, and reimbursement of medical interventions that best meet patients' needs, there is an increasing emphasis on patient-centred research. This type of research enga
A 68-year-old woman undergoing a routine surveillance endoscopy-part of her follow-up for a Barrett's oesophagus-was found to have a solitary, black lesion, approximately 4 mm in diameter, in the gast
Many adults diagnosed with a life-threatening condition have children living at home; they and their partners face the dual challenge of coping with the diagnosis while trying to maintain a parenting
HIV physician and PrEP campaigner. She was born in Leeds, UK, on May 27, 1974, and died of mesothelioma in Leeds, UK, on Feb 6, 2019, aged 44 years.
The birth of two gene-edited babies in November, 2018, in China has caused widespread concern and could have important social repercussions.1 Therefore, it is necessary and urgent to build a legal fra
Medicine depends on observation. Yet we are changing the way we look and that alters what we see. As a medical student, I was schooled according to a rigid mantra. Inspection, palpation, percussion, a
The announcement came as a surprise, prompting many to ask: Can the US FDA commissioner's policies continue without him? Susan Jaffe reports.
Following a communication from Harvard Medical School in 2014, we published an Expression of Concern1 about the above-referenced SCIPIO trial.2 We promised to inform readers when further investigation
One of the hardest things to do for any paediatrician is to talk with children or adolescents who have a potentially fatal illness about their diagnosis, treatment, and prognosis. There are many gener
The health and wealth of a nation are fundamentally linked. Healthier populations live longer, more productive lives, leading to greater economic prosperity. A report by the G20 Health and Development