Exploring the Benefits of Flexible Electronics for Medical Devices and Systems

Exploring the Benefits of Flexible Electronics for Medical Devices and Systems

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Description: MC10 takes rigid high-performance electronics and reshapes them into human-compatible form factors that stretch, bend and twist to move with the body. Data analysis, wireless transmission, informed decision-making. bio stamp motion+electromyography sensing surface electromyography multimodal sensing (motion + ECG + EMG) NFC-based epidermal electronics.

 
Author: Roozbeh Ghaffari PhD (Senior) | Visits: 552 | Page Views: 1038
Domain:  High Tech Category: Semiconductors 
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Contents:
EXPLORING the BENEFITS of FLEXIBLE ELECTRONICS for
MEDICAL DEVICES and SYSTEMS
Roozbeh Ghaffari, PhD
Co-Founder, Vice President of Technology
MC10 Inc., Cambridge, USA
Roozbeh GHAFFARI, PhD

BIOELECTRONICS AND THE HUMAN BODY

Roozbeh GHAFFARI, PhD

FUNDAMENTAL MISMATCH

6-Orders
of Magnitude
Difference in
HARDNESS

Hard | Rigid | Flat

Roozbeh GHAFFARI, PhD

Soft | Flexible | Curvy

MC10 takes rigid high performance
electronics

Roozbeh GHAFFARI, PhD

and reshapes them into
human-compatible
form factors that
stretch, bend
and twist
to move with the body

Roozbeh GHAFFARI, PhD

CORE TECHNOLOGY: EMBEDDED UNPACKAGED DIE

SIGNIFICANT REDUCTION IN THICKNESS
- Millimeter scale > microscale heights

Roozbeh GHAFFARI, PhD

SIGNIFICANT REDUCTION IN BENDING STIFFNESS
- Up to 9 orders of magnitude

CORE TECHNOLOGY: SPRING-LIKE INTERCONNECTS

Roozbeh GHAFFARI, PhD

EPIDERMAL BIOELECTRONICS “SECRET SAUCE”

Thinned
Oriented
Wood

Roozbeh GHAFFARI, PhD

Tissue paper

EPIDERMAL BIOELECTRONICS “SECRET SAUCE”

Thinned
Oriented
Wood

Tissue paper

Thinned

Silicon Wafer

Roozbeh GHAFFARI, PhD

Oriented

Flexible Silicon

Stretchable electronics

APPLICATIONS OF CONFORMAL ELECTRONICS

Smart Catheters
and Prosthetics

Roozbeh GHAFFARI, PhD

Cardiac Sensor
Sheets

Epidermal
Electronics

Paper-based
Sensors/Electronics

MINIMALLY-INVASIVE MEDICAL APPLICATIONS

Epicardial Sensor Sheets

Kim, Ghaffari et al, PNAS 2012
Roozbeh GHAFFARI, PhD

Instrumented Balloon Catheters

Kim, Lu, Ghaffari et al, Nature Materials 2011

APPLICATIONS OF CONFORMAL ELECTRONICS

Smart Catheters
and Prosthetics

Roozbeh GHAFFARI, PhD

Cardiac Sensor
Sheets

Epidermal
Electronics

Paper-based
Sensors/Electronics

CRITICAL FEATURES FOR EPIDERMAL ELECTRONICS

SPORTS &
FITNESS

CONSUMER
HEALTH

MEDICAL
DIAGNOSTICS

Roozbeh GHAFFARI, PhD

Rugged, durable, sweat resistant, comfortable, mechanically
invisible, location independent

Soft, discreet, durable, comfortable, body/skin-compatible
seamless high-quality sensing anywhere on the body

Accurate biofeedback, comfortable, discreet
Drives higher compliance, accurate measurements anywhere
on the body

WEARABLES MARKET SNAPSHOT

Roozbeh GHAFFARI, PhD

MOVING BEYOND THE WRIST…

Roozbeh GHAFFARI, PhD

THE BODY ENVIRONMENT
HEART RATE

SLEEP PATTERNS
ACTIVITY
UV LIGHT EXPOSURE

MUSCLE ACTIVITY

Roozbeh GHAFFARI, PhD

Roozbeh GHAFFARI, PhD

Sensors

Microprocessor

Flash Memory

Wireless Connectivity
(BTLE)

Battery

Roozbeh GHAFFARI, PhD

DATA ANALYSIS, WIRELESS TRANSMISSION, INFORMED
DECISION-MAKING
wireless connectivity

seamless sensing

continuous data
analysis

informed consumer, patient, caregiver, and/or HCP

Roozbeh GHAFFARI, PhD

Integration of novel sensors onboard BioStamp
(ECG, EMG, HR, Accel, Gyro, Temp, Sweat Loss)
Wearable
Sensor Patch

Adhesive
sticker

Charging
Platform

Mobile
phone
with
Application

Roozbeh GHAFFARI, PhD

BIOSTAMP MOTION+ELECTROMYOGRAPHY SENSING

Roozbeh GHAFFARI, PhD

SURFACE ELECTROMYOGRAPHY

Blue waveform: Lifting 1 lb,

Red Waveform: Lifting 5 lbs

Ghaffari et al, IEEE 2014
Roozbeh GHAFFARI, PhD

MULTIMODAL SENSING (MOTION + ECG + EMG)

Roozbeh GHAFFARI, PhD

NFC-BASED EPIDERMAL ELECTRONICS

Kim, Banks, Ghaffari et al, SMALL 2015
Roozbeh GHAFFARI, PhD

THERMAL MAPPING

Webb et al, 2013

Webb, Balooch et al, PLOSOne 2015
Roozbeh GHAFFARI, PhD

SKIN CONDUCTIVITY (HYDRATION) MAPPING

Ghaffari, Rogers et al, In Preparation
Roozbeh GHAFFARI, PhD

MAPPING MECHANICAL PROPERTIES

Dagdeviren, Ghaffari et al, Nature Materials 2015
Roozbeh GHAFFARI, PhD

ULTRA-VIOLET LIGHT SENSING

Rogers, Balooch, Ghaffari et al, In Preparation
Roozbeh GHAFFARI, PhD

MULTIMODAL SENSING AND ACTUATION

Son, Ghaffari, Kim et al, Nature Nanotechnology 2014

Roozbeh GHAFFARI, PhD

OPPORTUNITIES IN HEALTHCARE
Self Reported Patient Data

E. Steinbart Artwork
Roozbeh GHAFFARI, PhD

REAL-TIME BIOMETRIC (CLINICAL) DATA

Roozbeh GHAFFARI, PhD

REAL-TIME BIOMETRIC DATA + THERAPEUTICS
Sensor-Laden BioStamps
Transdermal Drug Delivery Patches

Son, Ghaffari, Kim et al, Nature Nanotechnology 2014
Roozbeh GHAFFARI, PhD

EPIDERMAL ELECTRONICS: BRIDGING THE GAP

BioStamp

Roozbeh GHAFFARI, PhD

EXPLORING the BENEFITS of FLEXIBLE ELECTRONICS for
MEDICAL DEVICES and SYSTEMS
Roozbeh Ghaffari, PhD
Co-Founder, Vice President of Technology
MC10 Inc., Cambridge, USA
Roozbeh GHAFFARI, PhD

Body On-board Diagnostic Systems “bODS”
BioStamp™: Powerful, location agnostic, physiological monitoring and insights

Analytical & Intelligent

Versatile & Comfortable

Medical-grade sensing &
insights

Disease and patient specific
body-location placement for
enhanced accuracy

Reliable & Durable
Designed to withstand the
rigors of daily life and activity

WiSP™:Complementary passive electronic tattoo

Extremely Thin
& Breathable
35

Customizable
MC10 CONFIDENTIAL

Extensible