360 Stem Cell & Regenerative Medicine Newsletter- April 02, 2015

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360 Stem Cell & Regenerative Medicine Newsletter - April 02, 2015

Featured Video :Stem Cell Connectivity {Duke University Research}

“A Duke University team has discovered how stem cells build long, slender structures that may ferry signals from one place to another, connecting the stem cell to the critical information it needs about its neighbors and its environment. In a March 2015 paper, the team has demonstrated that the structures convey myosin molecules which are known to carry signaling molecules. Assistant research professor Joshua Snyder explains the work in this video.”


Xconomy: Japan’s Fujifilm Snaps Up Cellular Dynamics to Grow Stem Cell Business
“Cellular Dynamics International, an up-and-coming player in the stem cell field and one of Wisconsin’s more promising biotech companies, is being acquired by Fujifilm for $307 million in cash.” The Xconomy article provides insight on the international implications of this deal for the future development and full commercialization of iPSC technology.

World Stem Cell Summit

Memorial Sloan Kettering Blog: The Future of Cancer: Five Reasons for Optimism
Dr. Eve Kiesler provides the reasons why we are “on the cusp of a brighter era” with the advent of precision medicine, immunotherapy, cell-based therapy, epigenetic therapy and research into metastasis.

Wake Forest

Health Canal: Stanford Researchers Identify 'Bridge' State Necessary for Cellular Reprogramming
In a significant new study published in Nature, it is shown that that mature cells enter a unique transition state when being reprogrammed to iPS cells. Deconstructing the reprogramming process will help researchers better understand pluripotency. “This was completely unexpected,” said Marius Wernig, M.D., associate professor of pathology at the School of Medicine and a member of the Stanford Institute for Stem Cell Biology and Regenerative Medicine. “It’s always been assumed that reprogramming is simply a matter of pushing mature cells backward along the developmental pathway. These cells would undergo two major changes: They’d turn off genes corresponding to their original identity, and begin to express pluripotency genes. Now we know there’s an intermediary state we’d never imagined before.”

Mayo Clinic

The Asahi Shimbun: RIKEN Looks Forward with Former Kyoto University President as New Chief
Japan’s RIKEN is starting on the full path to recovery. “The new president of RIKEN vowed to turn it into a world-class research institute by putting the scandal over a scientist's discredited stem cell work behind it. Hiroshi Matsumoto, former president of Kyoto University who became the head of RIKEN on April 1, said the path to gaining that status lay in the reform efforts Riken has taken since the scandal involving Haruko Obokata emerged.” RIKEN is Japan's largest comprehensive research institution historically renowned for high-quality research in a diverse range of scientific disciplines. Founded in 1917 as a private research foundation in Tokyo, RIKEN has grown rapidly in size and scope, today encompassing a network of world-class research centers and institutes across Japan.


Sacramento Business Journal: UC Davis Scientists Win $7M in California Stem Cell Research Grants
“Dermatology professor Roslyn Rivkah Isseroff got a $5 million grant to continue research on wound care that uses stem cells to treat diabetic foot ulcers. And Diana Farmer, a professor and chair of surgery at the UC Davis Medical Center, got almost $2.2 million to continue work on a placental stem cell therapy for spina bifida, a common birth defect that causes paralysis and incontinence.”

To see the full list of the latest $25M round CIRM grants, click on the Stem Cell Agency’s media release here.


Health Canal: The Brain-Belly Connection: Scientists Find Key Genetic Triggers in Weight-Regulating Brain Cells
Is overeating all in your head? A research team, led by Malcolm Low, M.D., Ph.D. of the University of Michigan Medical School and Marcelo Rubinstein, Ph.D., of the University of Buenos Aires in Argentina reported that it has located brain triggers in mice and fish that controls when to eat, or stop eating. The study was published in the Proceedings of the National Academy of Sciences, and a recent paper in PLoS Genetics, the team reported their discoveries on genetic factors key to the brain cells, or neurons, called POMC cells.


Sun-Sentinel: Florida’s Akron Biotech Poised for Growth
Here is a profile piece on the up-and-coming RegMed company, Akron Biotech, led by the intrepid scientist and entrepreneur, Dr. Claudia Zylberberg.


UTSA Biologist John McCarrey Recognized for Showing Leadership in Advancing the Discipline of Reproductive Biology
John McCarrey, Professor of Biology in the UTSA College of Sciences, has been selected to receive the Distinguished Service Award from the Society for the Study of Reproduction.
McCarrey was recognized for demonstrating unselfish service and leadership in advancing the discipline of reproductive biology and will receive the honor at Annual Meeting of the Society for the Study of Reproduction. Dr. McCarrey's area of expertise is in reproduction, stem cells and regenerative medicine. His research focuses on the development, differentiation and function of mammalian germ cells. Additional research interests include mechanisms governing genetic integrity in germ and stem cells and the effects of cloning and assisted reproductive technologies on genetic integrity.

360 Newsletter Editor

Bernard Siegel
Executive Director
Genetics Policy Institute

Stem Cells and the Transformative Power of Hope-a TEDx talk by Bernard Siegel, Editor of 360 Newsletter

Domain: Medical
Category: Biology
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