360 Stem Cell & Regenerative Medicine Newsletter- July 14, 2014

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360 Stem Cell & Regenerative Medicine Newsletter - July 14, 2014

Featured Video: a patient’s perspective on a MS clinical trial:
Stemcells' promising news on spinal cord injury, AMD therapies
Patient advocate Jennifer Molson addresses the ISSCR, describing her inspiring journey as a participant in a multiple sclerosis, stem cell-based clinical trial.
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. According to the University of Wisconsin-Madison, a group led by stem cell researcher Igor Slukvin reported the discovery of two genetic programs responsible for taking blank-slate stem cells and turning them into both red and the array of white cells that make up human blood. The research was reported in the journal Nature Communications.
Featured video from TEDxLongwood: Len Zon on the “Hope and Promise of Stem Cells.”

In this 20-minute TEDx talk, Dr Zon, of Boston Children’s Hospital, provides an intriguing glimpse into his important research. Who knew that zebra fish could provide amazing insights? Dr. Zon’s utilizes the zebra fish model for understanding and developing treatments for human disease. He introduces “Casper the transparent fish.” For viewers less familiar with the complexity of stem cell research, this video is an eye-opener. Editor’s note: Len Zon was the first president of ISSCR and serves as a member of the GPI Science Advisory Board.
Salk Institute: No extra mutations in modified stem cells, study finds
“The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with any new technology, it brings with it both promise—the hope of fixing disease-causing genes in humans, for example—as well as questions and safety concerns. Now, Salk scientists have put one of those concerns to rest: using gene-editing techniques on stem cells doesn't increase the overall occurrence of mutations in the cells.” The results were published in the journal Cell Stem Cell.
3D Print.com: U.S. Army is researching 3D printing and its potential in facial reconstruction surgery
This is a useful article describing the goal of Armed Forces Institute for Regenerative Medicine (AFIRM) to utilize 3D print technology to quicken battlefield treatment and hard tissue replacement and regeneration.
The Guardian (blog): Retractions are coming thick and fast- it's time for publishers to act
The founders of Retraction Watch make the case that journal publishers must acknowledge the limitations of traditional peer review and fully embrace post-publication peer review. Recent stem cell retractions cited.
Washington Post: Injured Argentine winger Angel Di Maria may be resorting to unproven stem cell therapy
Some top professional athletes are resorting to unproven stem cell treatments. Lenny Bernstein, writer of the To Your Health Blog, reports that the outcomes of these treatments are seldom reported.

Cellular Dynamics awarded patents covering derivation of pluripotent stem cells from fresh or banked human blood samples
The company press release provided a quote from CEO, Bob Palay. He stated, “Derivation of iPSCs from blood has several advantages over other tissues: donors are already familiar with a standard doctor’s office blood draw, where only a small amount of blood is required; blood is easily accessible and not exposed to environmental influences, as skin is; and the hundreds of thousands of previously banked blood samples enable researchers to create human disease models from donors with known genotypic and phenotypic backgrounds. These patents cover the reprogramming of both fresh and banked blood, enabling our customers to access any samples in their research quest to improve healthcare.”

360 Newsletter Editor


Bernard Siegel
Executive Director
Genetics Policy Institute




Stem Cells and the Transformative Power of Hope-a TEDx talk by Bernard Siegel, Editor of 360 Newsletter

About GPI


The nonprofit Genetics Policy Institute (GPI) seeks to establish a positive policy, regulatory and societal framework to enable research to flourish, under the highest ethical and medical standards. We seek to accelerate the discovery and development of lifesaving cures and therapies to alleviate human suffering due to chronic and terminal afflictions. Visit Website.

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Bringing our World Together- the World Stem Cell Summit
Domain: Medical
Category: Biology

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