360 Stem Cell & Regenerative Medicine Newsletter- July 8, 2014

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360 Stem Cell & Regenerative Medicine Newsletter - July 8, 2014

Featured Video: A Vote for Stem Cells
Stemcells' promising news on spinal cord injury, AMD therapies
The $3 billion California Institute for Regenerative Medicine, the world's largest stem cell research agency, is funded by the state - not the federal government. Nature Video asked fans on their way to a Giant’s baseball game near CIRM's headquarters whether they will approve $5 billion more for the research.
World Stem Cell Summit Pre-Early Bird Rates End Friday
DON’T MISS OUT! Take advantage of pre-early bird discounts for lowest summer rates (expiring July 11 | Register Today) and secure the best arrangements as registration is now open for the 2014 World Stem Cell Summit, December 3-5, in San Antonio.
Nature-Stem cells: Hope on the line
Is it time to refuel Prop 71? Nature journalist, Erika Check Hayden, provides an insightful article about the present state of affairs at CIRM and some of the pros and cons relating to a possible 2016 ballot measure.
Harvard Gazette: New way to regrow human corneas
Harvard -affiliated researchers identified a way to enhance regrowth of human corneal tissue to restore vision, using a molecule that acts as a marker for hard-to-find limbal stem cells. The work holds promise for burn patients, victims of chemical injury, and others with damaging eye diseases. The research, published in the journal Nature, is also one of the first examples of constructing a tissue from an adult-derived human stem cell.
Nature: Cloned stem cells offer high fidelity
Is SCNT the third pillar of pluripotency? According to Dr. Shoukhrat Mitalipov, stem cells made by nuclear transfer seem more faithful to originals than are cells that have been reprogrammed. The research published in Nature compared genetically identical human stem cells made by different techniques and reveals differences in gene expression that might be important for medical research and for cell therapies.
Featured Video: Irving L. Weissman, MD, discusses websites advertising unproven stem cell therapies

Irving L. Weissman, MD, Director of the Institute of Stem Cell Biology and Regenerative Medicine at Stanford University School of Medicine, discusses websites advertising unproven stem cell therapies.
New Scientist: Stem cell treatment causes nasal growth in woman's back
Illustrating some of the risks of cell therapies is this cautionary tale from the New Scientist, reporting on an adverse outcome in a clinical trial in Portugal to a single patient receiving a treatment for spinal cord injury. Editor’s comment: Stem cells and regenerative medicine represent the dawn of a new era of treating and potentially curing devastating medical conditions. The path to cures is going to be tedious. There will be adverse outcomes along the way. I hate to think we might discover a way to cure a rodent of diabetes but it will take 20 years to deliver the treatment to humans, in part, because of unreasonable regulatory roadblocks or that scientists can’t agree on cell standards. All safe and ethical paths should be open. Patient advocacy and public pressure must be asserted effectively on a global front to increase funding for basic research, rewrite the rules to expeditiously deliver safe treatments and to encourage incentives for investment in these promising advanced technologies. Laboring more than a decade to advance public awareness has taught me not to place all hope on a single cell type, a single research lab or a just any entrepreneur or doctor with a good story. No one person has all the answers. Through converging technologies we are in the midst of a biomedical revolution and we don’t have time to waste because people are dying right now.

According to a study appearing in the journal Cell Stem Cell, researchers from the Johns Hopkins University School of Medicine have uncovered a new genetic variant that could result in certain people having a predisposition to schizophrenia.
The Rockefeller University: Using geometry, researchers coax human embryonic stem cells to organize themselves
According to a media release, “By monitoring specific molecular pathways the human cells use to communicate with one another to form patterns during gastrulation — something that was not previously possible because of the lack of a suitable laboratory model —researchers learned how specific inhibitory signals generated in response to the initial chemical cues function to prevent the cells within a colony from all following the same developmental path.” The research was published in Nature Methods.
Dental pulp stem cells promote the survival and regeneration of retinal cells after injury
Researchers at the University of Birmingham, UK, discovered that stem cells isolated from the teeth, termed dental pulp stem cells (DPSC), can protect retinal ganglion cells (RGCs) from death following injury and promote regeneration of their axons along the optic nerve. The research was published in Neural Regeneration Research.
The Guardian: 3D printed organs come a step closer
In findings published in the journal of the Royal Society of Chemistry, researchers from Sydney and Harvard universities have managed to 3D bio-print capillaries, the tiny channels that allow vascularisation to take place so that cells can sustain themselves and survive.
StemCells, Inc. appoints Dr. Alan Trounson to board of directors
Dr. Trounson most recently served as President of The California Institute of Regenerative Medicine (CIRM). He also is one of the founding members of the Scientific Advisory Board of the Genetics Policy Institute (GPI), the publisher of this 360 Newsletter.

360 Newsletter Editor

Bernard Siegel
Executive Director
Genetics Policy Institute

Stem Cells and the Transformative Power of Hope-a TEDx talk by Bernard Siegel, Editor of 360 Newsletter

About GPI

The nonprofit Genetics Policy Institute (GPI) seeks to establish a positive policy, regulatory and societal framework to enable research to flourish, under the highest ethical and medical standards. We seek to accelerate the discovery and development of lifesaving cures and therapies to alleviate human suffering due to chronic and terminal afflictions. Visit Website.

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Category: Biology
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