360 Stem Cell & Regenerative Medicine Newsletter- November 04, 2014

 Manjesh Singh

360 Stem Cell & Regenerative Medicine Newsletter - Nov 04, 2014

Featured Video : Latest “Stem Cell Shorts”- Cancer Stem Cells:
what is a cancer cell
Canada’s Ben Paylor of Signals reports, “Just over one year ago, we launched the pilot phase of an animation project titled StemCellShorts here on Signals blog. Funded by a Stem Cell Network Public Outreach Award, the project was very much an experiment for us to see what would happen when you tasked a team of talented creatives, expert faculty and some eager graduate students with a public engagement challenge. With almost 40,000 online views over the last year and awards from several major international science communication competitions (including a feature in the February 2014 issue of Science), StemCellShorts is quickly becoming a powerful new medium in this powerful new world of science.” Ben is also a 2013 World Stem Cell Summit Poster Forum winner
University of Texas Health Science Center at San Antonio to teach "Stem Cells 101" at free Education Day with World Stem Cell Summit on Tuesday, December 2, 2014
In a news release breaking this morning, Genetics Policy Institute (GPI) announced they have partnered with the University of Texas Health Science Center at San Antonio to offer a Public Education Day on December 2, one day before the 10th annual World Stem Cell Summit #WSCS14, December 3-5. The Stem Cells and Regenerative Medicine Public Education Day is free and open to the public. Attendees will learn about the latest scientific breakthroughs, experience hands-on lab activities, discover how stem cell discoveries translate into medicine, and get the tools they need to protect their family from the risks of unproven, unsafe stem cell treatments. Experts will discuss new applications for stem cells in diabetes, cancer, wound care, neurological and muscle disorders, and other conditions. The Public Day will kick-off with a special lecture provided by world-renowned researcher, Elaine Fuchs, Ph.D, an endowed professor at Rockefeller University, member of the Institute of Medicine and National Academy of Sciences, and past president of the International Society for Stem Cell Research (ISSCR).
Advancing the Science of Cord Blood Stem Cell Therapy
Bioscience Technology: World-first embryonic stem cell trial for the heart
In an excellent article by science writer Cynthia Fox, she discusses two alternative cell therapy approaches to severe heart disease. Both use human embryonic stem cells.

The first embryonic stem (ES) cell trial for severe heart failure is launching now in Paris. INSERM’s Dr. Phillipe Menasche, will lead the trial utilizing cardiac progenitor cells made in a lab from human embryonic stem cells to six patients.

The article also discusses an alternative approach presented at the recent meeting of the New York Stem Cell Foundation. At that meeting, University of Washington cardiologist and stem cell researcher Chuck Murry presented strong evidence that more mature— if not fully mature— cardiomyocytes from embryonic stem cells can themselves form new cardiac muscle when injected directly into hearts of monkey’s post-myocardial infarction.
Synthecon 3D technologies for Stem Cell Cultures
The Verge: Tiny human stomachs have been created from stem cells- they look 'more like a mini-organ than anything else that’s ever come before'
Researchers at Cincinnati Children’s Hospital have created three-dimensional “mini-stomachs” from human embryonic stem cells. According to The Verge, “The researchers in this study were able to look at what happens when bacteria encounters ‘healthy’ gastric tissue in a Petri dish. The new technique might one day help them identify the genes and cell signaling patterns that allow bacteria like Helicobacter pylori — the primary cause of peptic ulcer disease — to wreak havoc in our gastrointestinal tracts. The gastric tissues could also enhance the way pharmaceutical companies test the drugs that treat infections. Since stomach cancer is the second leading cause of cancer-related deaths, investigating how these sorts of cancer precursors develop might one day help extend patients’ lives.” The research was published in the journal Nature.
RegMedNet Join our online community
Cedars-Sinai: Lou Gehrig's Disease study- renewing brain's aging support cells may help neurons survive
“With publication of a study by investigators at the Cedars-Sinai Board of Governors Regenerative Medicine Institute, ALS researchers know the effects of the attack are worsened, at least in part, by the aging and failure of support cells called astrocytes, which normally provide nutrients, housekeeping, structure and other forms of assistance for neurons. Earlier studies suggested the possible involvement of these support cells in ALS development and progression, but the new research is believed to be the first to directly measure the effects of aging on the ability of astrocytes to sustain motor neurons.” The results were published online in Neurobiology of Aging. The study’s senior author is Clive Svendsen, PhD, professor and director of the Institute.
Coriell Institute for Medical Research
PostBulletin.com: No hitches thus far in Mayo Clinic’s ALS stem cell trial utilizing adipose tissue
Mayo Clinic’s adipose tissue stem cell trial aimed at treating ALS continues. This update includes comments from Dr. Nathan Staff and Dr. Anthony Windebank, both featured speakers at the upcoming World Stem Cell Summit in San Antonio.
UT-San Diego: WARF patent saga continues- Stem cell patent dispute to reach U.S. Supreme Court
The U.S. Supreme Court will be asked to intervene over a highly disputed embryonic stem cell patent. Dr. Jeanne Loring, a stem cell scientist at The Scripps Research Institute, leads the attack. The Supreme Court is being asked to overturn a lower court decision and allow the opponents to seek cancellation of the patent held by the Wisconsin Alumni Research Foundation, or WARF.
Hogan Lovells working with life science clients
Irish Examiner: Lab-grown stem cell trial (MSC’s) gets green light in Ireland
Ireland’s first human stem cell trial using lab-grown cells is due to get underway in Galway in 2015 following approval from the regulatory agency. The trial will involve extracting adult mesenchymal stem cells (MSC’s) from the bone marrow of patients with critical limb ischemia (CLI) — a severe blockage of the arteries resulting in marked reduction in blood flow to the extremities. The research is focused on whether MSC therapy could improve blood flow to the legs in patients with CLI — a condition common in diabetics — and therefore avoid the need for amputation. The trial is aimed predominantly at testing the safety and feasibility.
BioNews Texas: Stem cells can repair osteoarthritis damage via microscaffolding
Bioengineering professor Liping Tang at the University of Texas, Arlington is the recipient of a $1.04 million grant from the United States Army to fund his work on using injectable, biodegradable microscaffolding to facilitate enhanced cartilage and bone healing using autologous stem cell transplant technology.
According to Dr. Tang, “We’ve found that if we inject microscaffolding that we’ve developed into the injured area, it can trigger the stem cell generation needed for proper healing.”
wafsf conference

360 Newsletter Editor

Bernard Siegel
Executive Director
Genetics Policy Institute

Stem Cells and the Transformative Power of Hope-a TEDx talk by Bernard Siegel, Editor of 360 Newsletter
Domain: Medical
Category: Biology

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