360 Stem Cell & Regenerative Medicine Newsletter- November 20, 2015

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360 Stem Cell & Regenerative Medicine Newsletter - Nov 20, 2015

Featured video NBC Channel 7 San Diego:

2-Year-Old With Cerebral Palsy Walking After Stem Cell Infusion
The featured video tells the story of a little 2-year-old San Diego girl who received a stem cell infusion of her own umbilical cord blood, banked at birth, is giving new hope to parents of children with brain injuries. Doctors have used cord blood for decades to help with blood disorders and some other diseases, but now a handful of new studies show those same cells can travel up to a baby’s brain and heal injured areas. The child received the infusions at Duke University as part of the groundbreaking work of Dr. Joanne Kurtzberg. 360 Note - Dr. Kurtzberg is a featured speaker at the World Stem Cell Summit in Atlanta next month. The cerebral palsy grassroots community, represented by Cure CP , will be recognized at the Summit as one of the “Stem Cell Action Award” honorees.

World Stem Cell Summit

The Japan Times: Government to Set Safety Guidelines for iPS Cells Clinical Study- Insurance Reimbursement
Japan’s health ministry announced that it will draw up safety guidelines for clinical study using induced pluripotent stem (iPS) cells by March 2016. In additional news, the Central Social Insurance Medical Council of Japan’s health ministry approved public insurance coverage for two regenerative medicine products. The council extended insurance coverage to regenerative medicine for the first time since the pharmaceuticals and medical equipment law took effect in 2014. The approved items are “HeartSheet” cell sheets and “Temcell” stem cell-based drug.

UPDATE: World Stem Cell Summit & RegMed capital Conference

Poster abstract submission deadline extended to November 30. Register today!

See speakers.
New panels! See agenda.
See updated sponsor page.

Read Summit Media Advisory - click here.

Biological Industries

Tech Times: Stem Cell Discovery Could Lead To Effective Treatments For Duchenne Muscular Dystrophy
In a study published in Nature Medicine, a group of Canadian researchers showed for the first time that muscle stem cells are directly affected by Duchenne muscular dystrophy, which could translate to better treatment of the degenerative disease. The lead scientist is Dr. Michael Rudnicki, a University of Ottawa professor and regenerative medicine director at Ottawa Hospital. He is optimistic about finding far more effective treatments for the condition.

Chart MVE

iPolitics: Canada Needs to Put its Money Where its Future Is: Stem Cell Research
One of Canada’s leading scientists, Dr. Michael Rudnicki, points out that the Canadian Stem Cell Network will run out of funds within 12 months, to the detriment of human health and the nation. In his opinion, “The Trudeau government should be applauded for appointing a full-standing minister of Science. This is a welcome development in a country that hasn’t been celebrated enough for its contributions to the global scientific research enterprise. One area of research that is particularly underfunded in Canada is, ironically, one that can start making a drastic difference in the health of Canadians and people around the world: stem cell research and personalized medicine.”

Bridge to life

Independent: 'Voice Transplants' One Step Closer After University of Wisconsin Scientists Grow Human Vocal Chords
“Human vocal cords have been grown in the laboratory for the first time in a development that could one day lead to ‘voice’ transplants for people who cannot speak because of a permanently damaged larynx. Scientists said that the bioengineered vocal cords grown from individual cells produced sounds similar to those made by the human voice box when warm, moist air was passed over them to make them vibrate. The researchers believe that it may be possible to generate a variety of synthetic vocal cords which can be used ‘off the shelf’ for transplant operations to suit the individual needs of different patients who cannot speak.” The research from the University of Wisconsin-Madison was published in the journal Science Translational Medicine.

Cyfuse

South China Morning Post: Some Mothers Do 'ave 'em: Mice with Two Mums Bred in China
“Scientists in Shanghai are rewriting the rules of reproduction with a groundbreaking experiment that combined genetic material from two female mice to create healthy offspring, according to a paper in Cell Research. But the researchers said they strongly opposed using the technology to create humans, saying it would give rise to serious ethical and genetic problems. The team, led by Professor Li Jinsong from the Chinese Academy of Sciences’ Institute of Biochemistry and Cell Biology, genetically modified ovum-derived embryonic stem cells to make them function like sperm, and injected the cells into ova to produce a batch of mouse pups with two genetic mothers. ‘The entire process does not require any male involvement,’ Li said. ‘Sperm is replaceable – that’s clear from the experiment.’” 360 Editor’s comment: Dear readers, that is the actual headline of the article. I can’t make this stuff up. Articles like this are like a dose of “Future Shock” with your morning coffee.

Casis

The New Yorker: Can CRISPR Avoid the Monsanto Problem?
Michael Spector has written a first-rate opinion piece on CRISPR- the powerful gene editing technology. I agree with Spector’s observations. “To deploy CRISPR properly will require far more than a dialogue among scientists, however, no matter how public or well-intended. Many of the people I interviewed told me that, if the public is left out of the discussion about CRISPR, the technology will almost certainly end up with what they described as a ‘Monsanto problem.’ When Monsanto introduced G.M.O.s, in the nineteen-nineties, it failed to engage people. Nobody knew whether these new products—seeds created in a lab—were safe, or for whom they were most valuable. The result was a suspicion (and, in many cases, an overt hostility) that has lingered long after the technology has been proven both safe and useful. CRISPR is far too important to become entangled in the same web of confusion that has made G.M.O.s such a toxic issue. We ought to have learned something from those troubling and extended shouting matches; scientists, politicians, and everyone else needs to join in on this debate now. Society has no choice but to come to terms with both the potential benefits and the possible risks. That will require a big change: today, there isn’t even really a regulatory mechanism capable of governing products like CRISPR.”

CCRM

Nova Southeastern University (Florida) Announces New NSU Cell Therapy Institute, an International Biomedical Research Collaboration with Scientists from the World-Renowned Karolinska Institutet
“Nova Southeastern University (NSU) is now at the forefront of conducting pioneering cell-based biomedical research with the launch of the new NSU Cell Therapy Institute, an international collaboration with prominent medical research scientists from Sweden's world-renowned Karolinska Institutet (KI). KI is globally recognized for its Nobel Assembly, which awards the Nobel Prize in Physiology or Medicine annually. The Institute will be located in NSU's soon-to-be-completed, 215,000 sq. ft. Center for Collaborative Research (CCR), one of the largest and most advanced research facilities in Florida, with state-of-the-art laboratories. The NSU Cell Therapy Institute is dedicated to the discovery and development of innovative translational biomedical research, focused on the potential of cell-based therapies to prevent, treat and cure life-threatening and debilitating diseases. The Institute is accelerating the advancement of next-generation approaches to precision medicine such as targeted immunotherapy and regenerative medicine with an initial focus on targeting cancers, and heart disease and disorders causing blindness.”

CBR

Fansided: UFC’s Conor McGregor Took Stem Cell Injections Before Fighting Chad Mendes
“Most men don’t fight on a torn ACL, but most men aren’t Ultimate Fighting Champion (UFC) interim featherweight champion Conor McGregor. Earlier this month, McGregor shared that he had torn 80 percent of his ACL, and was competing with the injury when he took to the cage against Chad Mendes at UFC 189. According to Emory Healthcare, it takes four to six months to possibly return to athletic competition, but UFC president Dana White said that the outspoken Irishmen took an unconventional approach to his recovery.”

To the journalist’s credit he added this disclaimer, “The use of stem cell injections has seen some promise from the scientific community but has yet to illicit any response considering it a better option to traditional ACL reconstruction. A 2014 article in the journal Arthroscopy and Sports Medicine says that despite success stories in animal models, there hasn’t been any concrete evidence presented that suggests stem cell injections will become standard.”

Stem Cell Podcast

360 Newsletter Editor

Bernard Siegel
Executive Director
Genetics Policy Institute




2015 World Stem Cell Summit

About GPI

The nonprofit Genetics Policy Institute (GPI) seeks to establish a positive policy, regulatory and societal framework to enable research to flourish, under the highest ethical and medical standards. We seek to accelerate the discovery and development of lifesaving cures and therapies to alleviate human suffering due to chronic and terminal afflictions. Visit Website.

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