360 Stem Cell & Regenerative Medicine Newsletter- October 22, 2014

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360 Stem Cell & Regenerative Medicine Newsletter - Oct 22, 2014

Featured video: BBC: Paralyzed man walks again after stem cell transplant
Paralyzed man walks again after stem cell transplant
A new era dawns in the treatment of paralysis. This is a big global story. BBC journalist Fergus Walsh provides an excellent summary of this astounding cell transplant breakthrough. A man paralyzed since 2010 is able to walk again after a pioneering therapy in Poland that involved surgically transplanting cells from his nasal cavity into his spinal cord. Prof Geoff Raisman, chair of neural regeneration at University College London's Institute of Neurology, led the UK research team. He said what had been achieved was "more impressive than man walking on the moon". The study was reported in the journal Cell Transplantation.
The Alliance for Regenerative Medicine (ARM) and the Alliance for Advanced Therapies (AAT) merge to create one unified voice for next generation therapies in Europe and the U.S.
The Alliance for Regenerative Medicine (ARM), along with its European sister organization, the Alliance for Advanced Therapies (AAT), announced the approval of a Memorandum of Understanding to merge the membership of AAT into ARM. The result of this membership merger is the creation of one global organization operating on behalf of the advanced therapies and regenerative medicine sector (cell therapy, gene therapy and tissue engineering) in both the U.S. and Europe. According to the ARM media release, “ARM hosts events in the U.S. and Europe to bring together emerging companies, large pharma, investors, research institutes, government agencies and medical philanthropies that provide opportunities to build awareness of new developments and encourage collaborative relationships.”
Newborn Possibilities program CBR
Pitt/McGowan Institute team discovers stem cells in the esophagus
“Despite previous indications to the contrary, the esophagus does have its own pool of stem cells, said researchers from the University of Pittsburgh School of Medicine in an animal study published online in Cell Reports. The findings could lead to new insights into the development and treatment of esophageal cancer and the precancerous condition known as Barrett’s esophagus.” Dr. Eric Lagasse, associate professor of pathology, Pitt School of Medicine, and director of the Cancer Stem Cell Center at the McGowan Institute for Regenerative Medicine, led the study.
Newborn Possibilities program CBR
Children’s Hospital Los Angeles: First step- from human cells to tissue-engineered esophagus
“In a first step toward future human therapies, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have shown that esophageal tissue can be grown in vivo from both human and mouse cells. The study has been published online in the journal Tissue Engineering, Part A. The tissue-engineered esophagus formed on a relatively simple biodegradable scaffold after the researchers transplanted mouse and human organ-specific stem/progenitor cells into a murine model, according to principal investigator Dr. Tracy C. Grikscheit.”
The GID group, inc.
MTV Hive: Interview with Pearl Jam’s Eddie Vedder on supporting stem cell research to heal EB
Rock star Eddie Vedder supports a non-profit called Heal EB, which raises awareness about Epidermolysis Bullosa, a painful congenital disease that causes blisters after the mildest trauma. According to Eddie, “Because of major advances in stem cell research, the non-controversial kind, it appears that a cure could someday be a reality. But only if the good doctors and researchers can acquire further funding, whether privately or through our government.”
Stem Cell Research
Akron Biotech expanding to new, state-of-the-art biotechnology facility
“Akron Biotech which provides novel technologies for cell therapy and regenerative medicine discovery, development, and commercialization, announced its expansion and move to a new, larger facility. Akron will continue to be headquartered in Boca Raton, Florida while significantly increasing space for its R&D and manufacturing operations. The augmented capacity will further expand Akron's proven expertise in cGMP product manufacturing and process development, providing its customers with greater flexibility in manufacturing and enhanced environmental control as well as increased support for documentation and compliance.”
Crain’s Detroit Business: Asterand ready to grow as it moves HQ back to Detroit- an upshot of sale of Stemgent stem cell operations to ReproCELL
“Stemgent Inc., a Massachusetts-based company that sells products to the stem cell industry, including lines of stem cells, decided to diversify its business two years ago by buying Detroit-based Asterand plc, a tissue bank company that supplies researchers around the world.
Stemgent's investors liked the tissue bank business so well they have decided to undiversify. In September, they announced the sale of the stem cell operation to ReproCELL of Yokohama, Japan, for $8.5 million in cash. On Oct. 1, Stemgent announced the deal had closed and that the company had been renamed Asterand Bioscience Inc.
Bioscience Technology: Embryonic stem cells in trial for diabetes
If you are trying to absorb the impact of the recent advances utilizing human embryonic stem cells and diabetes, I recommend this article by journalist Cynthia Fox, in which she succinctly explains the recent work at Harvard Stem Cell Institute and the Viacyte clinical trial.
Irvine Scientific
KCUR.org: Why Missouri doesn't offer angel tax credits to startup investors? Answer: stem cells!
“The Missouri House of Representatives passed angel investor legislation in the most recent session, but it didn't advance in part because of a controversial amendment tacked on to bar investment in companies that do stem cell research. Lobbying group Missouri Right to Life threatened to oppose the bill and others like it without the language.”

360 Newsletter Editor

Bernard Siegel
Executive Director
Genetics Policy Institute

Stem Cells and the Transformative Power of Hope-a TEDx talk by Bernard Siegel, Editor of 360 Newsletter
Domain: Medical
Category: Biology

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