Creative Biolabs has been dedicated for years to providing advanced antibody products for the clients worldwide assisting with their problems on aspects of CRC cancer research and related therapy development. The products that cohere the accumulated experience and concentrated exploration of dedicated scientists would definitely meet the high laboratory requirements.
Regarded as the 2nd largest cancer killer in the western world, colorectal cancer has always remained a headache in the medical area of which the effective therapy and precise diagnosis are in urgent demand. Study indicates that 25% of the patients have family CRC background. Due to the fact that up to 5 percent of CRC cases are caused by single gene mal variation, hence detecting the signaling pathway is quite crucial, which include Wnt signaling, receptor tyrosine kinase (RTK) signaling, TGFβ and TNF-α signaling, etc. Creative Biolabs offers the comprehensive recombinant antibodies countering the above-mentioned cascades.
1. Signaling cascades
The gene family of WNT has been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Targeting at the Wnt signaling pathway that is activated by Wnt ligands, the Anti-WNT1 antibodies are readily available to fulfill customers’ project as strong support. The various designed antibodies can be applied to tests like ELISA, Flowy Cytometry, Immunocytochemistry, Immunofluorescence, etc. To satisfy the majority of the projects’ objectives, those antibodies cross-react among humans, mice, and rats, etc. The RTK signaling cascades mainly consist of VEGFR, IGFR1, PI3K, EGFR, and MET, which if changed, can affect the proliferation, diversion, survival and cell migration.
2. Targeted therapies
Over the decades, the number of the directional drugs increases dramatically bringing hope to patients held up by CRC. Different from other companies that only provide limited antibody products during the detecting stage of CRC, Creative Biolabs also offer ones that are applicable to the research work of target therapies, including Anti-CREB antibodies, which can be utilized to induce the production of the Creb-binding protein that principally applies to the research of the mCRC therapy for Wnt pathway.
Colorectal cancer, also known as colon cancer or bowel cancer, mainly manifests symptoms like changing bowel movement, weight loss and hematochezia, etc. An increasing number of medical institutes and pharmaceutical manufacturers concentrates on the targeted therapies. Creative Biolabs is with no doubt a fine assistant that comprehensively facilitates clients’ projects. For details regarding the CRC research, please feel free to visit https://www.antibody-creativebiolabs.com/.
About Creative Biolabs
Since 2004, Creative Biolabs started working on offering high-quality services in academic and life science worldwide. As the leading role in discovering and manufacturing recombinant antibodies, advanced antibody research tools, professional technical support, and rapid global delivery are utilized to ensure quality for scientific research workers and customers in industry. A custom-service-centered business model is taken seriously for optimizing the drug development process, leveraging accessible resources, and gathering a team from various backgrounds to conduct drug discovery projects in the future.