Go to Page # Page of 7
loading

Beta Cells: A great target for Stem Cell Therapy?

 Alan Colman
  10th-Jun-2016
Description: Making pancreatic beta cells from pluripotent stem cells: Why? Unmet clinical need for all Type 1 and many Type 2 diabetics, Proof of Concept established with Edmonton protocols, No need for physical integration of transplanted cells and relatively facile transplantation, BUT Large cell dose needed (10 8 -10 9 beta cells), Must be allogenic for Type 1, Challenging and expensive differentiation, Healthcare economics contentious. Making human pancreatic beta cells from pluripotent stem cells: A selected chronology- 1998: Human ES cell (hESC) lines established(Thomson et al), 2001: Spontaneous differentiation of ins+ cells in hESC embryoid bodies (Assady et al)..
Views: 996
Domain: Medical
Category: Biotech/Pharma
Contributing Organization: World Stem Cell Summit
 ‐ More of their Presentations
Contents:
Beta Cells: A great target for stem cell
therapy?
Alan Colman
Genea Biocells (Sydney/San Diego) and Harvard
Department of Stem Cells and Regenerative Biology,
Cambridge, USA.
World Stem Cell Summit Dec 12 2015
Disclosure: Member of the SAB for Semma Inc, Cambridge, USA

Making pancreatic beta cells from pluripotent
stem cells: Why?
• Unmet clinical need for all Type 1 and many Type 2 diabeti ... See more

Recent Presentations

...
21 September, 2019
Yoojin Oh
20 September, 2019
...
19 September, 2019