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Darwinian Medicine - examples of evolution applied to human health

 University of British Columbia
  13th-Jan-2017
Description: The application of Darwinian concepts like phylogeny, natural selection, etc. to medical problems and treatments.Bilirubin is a yellow breakdown product of heme catabolism. Accumulates when there is liver failure resulting in jaundice. Excreted via bile after it is made water soluble in the liver = proximate. The distinction between evolutionary and proximate questions: Low-density lipoproteins (LDLs) transport cholesterol to the arteries and when LDL is oxidized it is retained by the arteries creating plaques - atherosclerosis> heart disease. One risk factor for heart disease = elevated levels of LDH. The oxidation of LDH can be prevented by water and lipid soluble anti-oxidants. Bilirubin is a molecule that protects against oxidative damage.
Views: 1109
Domain: Medical
Category: Biology
Contents:
Darwinian Medicine
Learning objectives:
1.

Defining proximate vs. evolutionary mechanisms
and questions.

2.

Identifying the targets: universal traits or genes,
pathogens, cells.

3.

Cool examples of evolution applied to human
health.
Bio 336-week13

1

Darwinian medicine
Definition:
The application of Darwinian concepts like
phylogeny, natural selection, etc. to medical
problems and treatment ... See more

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