Adaptive Role of weak magnetic fields in Modulating Metabolic Pathways in Spheroid forming Prostate Cancer Cells

 Mazhar Sher, Saheed O. Oseni DVM MS, Evan Clark, Mirjana Pavlovic MD PhD, James Kumi diaka DVM MS Ph
  22nd-Apr-2017
Description: This study evaluates the role of extremely low frequency weak magnetic fields in prostate cancer stem cells. The aim is to develop a novel cancer therapy utilizing weak magnetic fields that do not induce any DNA damage to normal cells, but alter the membrane of cancer stem cells. The main focus is to design a purposely built, cost-effective and portable magnetic field exposure system using multiple coils to observe the effect of in-vitro radiations in the modulating metabolic pathways. The magnetic radiations of 0.5 mT at two different frequencies i.e. 1 Hz and 1 KHz for short intervals of time are incorporated to induce cell death in prostate cancer stem cells. The low magnetic field (applied in an evacuated chamber) exerts a mechanical disruption of cell membrane with its death as a final effect.
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Domain: Medical
Category: Equipment
Contributing Organization: World Stem Cell Summit
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Contents:
Adaptive Role of weak magnetic fields in Modulating Metabolic Pathways in Spheroid forming
Prostate Cancer Cells
Topic
Basic Research, Medicine, and Health
Author(s)
Mazhar Sher
PhD Student
Florida Atlantic University USA
Co-Author(s)
Saheed O. OseniOseni, D.V.M., M.S. – PhD student, Florida Atlantic University
Evan Clark, BS Biology – Masters Student, FAU
Mirjana Pavlovic, MD PhD &nda ... See more

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