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Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation

 The New England Journal of Medicine
Description: We originally designed the trial to test whether long-term treatment with supplemental oxygen would result in a longer time to death than no use of supplemental oxygen among patients who had stable COPD with moderate resting desaturation (oxyhemoglobin saturation as measured by pulse oximetry [Spo2], 89 to 93%). After 7 months and the randomization of 34 patients, the trial was redesigned to also include patients who had stable COPD with moderate exercise-induced desaturation (during the 6-minute walk test.
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new england
journal of medicine

established in 1812

October 27, 2016

vol. 375  no. 17

A Randomized Trial of Long-Term Oxygen for COPD
with Moderate Desaturation
The Long-Term Oxygen Treatment Trial Research Group*​​

a bs t r ac t

Long-term treatment with supplemental oxygen has unknown efficacy in patients with
stable chronic obstructive pulmonary disease (C ... See more

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