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Liquid Biopsy, Present and Future

 Laura Muinelo Romay
  11th-Oct-2017
Description: Concordance of Anaplastic Lymphoma kinase (ALK) gene rearrangements between circulating tumor cells and tumor in one-small cell lung cancer. Potential role nuclear PD-L1 expression in cell-surface vimentin positive circulating tumor cells as a prognostic marker in cancer patients. Clinical significance of Androgen Receptor Splice variant-7 mRNA Detection in circulating tumor cells of men with metastatic castration-resistant prostate cancer treated with first and second line abiraterone and enzalutamide.
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Domain: Medical
Category: Therapy
Contents:
Liquid Biopsy, present and future
LAURA MUINELO ROMAY,
LIQUID BIOPSY ANALYSIS UNIT,
ONCOMET, IDIS, SANTIAGO DE COMPOSTELA
SANTANDER 13-7-2017

Liquid Biopsy

What are we looking for?

Siravenga et al., Nature Rev 2017

Liquid Biopsy advantages

PAST
Circulating tumour cells (CTCs)

•T.R. Ashworth,
Austrian
Medical
Journal, 14:
146, 1869.

Stephen Paget, 1889

PAST

Cell-free DNA (cfDNA)
... See more

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