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Hematopoiesis: Stem Cells

 Evan Ingley PhD
  13th-Feb-2018
Description: Niche cells (green) underlying a basement membrane signal to stem cells (red) to block differentiation and regulate division. When a lineage mechanism prevails (lower mitotic cell), the stem cell divides such that one daughter retains its connections to the niche, while the other (yellow) becomes untethered and begins to differentiate.
Views: 1021
Domain: Medical
Category: Biotech/Pharma
Contents:
Hematopoiesis: Stem Cells

Dr. Evan Ingley
WAIMR
eingley@waimr.uwa.edu.au
WAIMR

Overview
• Hematopoiesis - development from stem cell
• Definitions / type / identification of stem cells
• The stem cell environment - isolation culture
• HSC self renewal
• HSC signaling pathways - gene expression
• HSC during development
• Cancer and the HSC
• HSC plasticity ... See more

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